Yes, it is possible to use `querySelectorAll()` to select all table cells that have a specific class within a specific row or column. To do this, you need to combine the row or column selector with the class selector.
Here's an example:
```html
<table id="myTable">
<tr>
<td class="myClass">1</td>
<td>2</td>
</tr>
<tr>
<td>3</td>
<td class="myClass">4</td>
</tr>
<tr>
<td class="myClass">5</td>
<td>6</td>
</tr>
</table>
```
Using JavaScript, you can select all table cells with class `myClass` in the first row like this:
```javascript
const firstRow = document.querySelector("#myTable tr:first-child");
const cells = firstRow.querySelectorAll("td.myClass");
```
And to select all table cells with class `myClass` in the first column, you can do the following:
```javascript
const cells = document.querySelectorAll("#myTable tr td:first-child.myClass");
```
Adjust the index for `:first-child` or use `:nth-child(n)` to target a different row or column.